The rate constant for the reaction of CH2ClBr with OH was measured by both flash photolysis resonance fluorescence and discharge flow electron paramagnetic resonance techniques over the temperature range 277-370 K. The Arrhenius expression (3.04 +0.8/-0.6)×10-12×exp{-(978 ± 72)/T} cm3molecule-1s-1 was derived from a composite fit to both data sets. Absorption cross-sections of CH2ClBr were measured from 187 to 290 nm at 295 K. The solubility of CH2ClBr in water was also estimated to determine if such a process could be important in determining the atmospheric lifetime of CH2ClBr. The atmospheric lifetime and ozone depletion potential for CH2ClBr were estimated.